ISOLATION OF α-AMINOBUTYRIC ACID FROM REDUCED THIOSTREPTON
نویسندگان
چکیده
منابع مشابه
y-aminobutyric acid
An enzyme which catalyses dehydrogenation of y-aminobutyraldehyde (ABAL) to y-aminobutyric acid (GABA) was purified to homogeneity from rat brain tissues by using DEAE-cellulose and affinity chromatography on 5'AMP-Sepharose, phosphocellulose and Blue Agarose, followed by gel filtration. Such an enzyme was first purified from mammalian brain tissues, and was identified as an isoenzyme of aldehy...
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Binding of [(35)S]thiostrepton to ribosomes from thiostrepton-sensitive and -resistant strains of Bacillus subtilis was studied. Ribosomes from thiostrepton-resistant strains bound relatively little thiostrepton compared with ribosomes from thiostrepton-sensitive B. subtilis. In addition, ribosomes from revertant strains that were obtained as thiostrepton-sensitive revertants from thiostrepton-...
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Introduction Gamma-aminobutyric acid (GABA) is a major neuro transmitter widely distributed throughout the central nervous system (CNS). Because too much excitation can lead to irritability, restlessness, insomnia, seizures, and movement disorders, it must be balanced with inhibition. GABA – the most important inhibitory neurotransmitter in the brain – provides this inhibition, acting like a “b...
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The quantitative measurement of amino acids in different areas of the central nervous system has shown that a progressive increase takes place in levels of y-aminobutyric acid during development (2, 3), and that the concentration of this amino acid in adult brain is relatively constant under a variety of physiological stresses. y-Aminobutyric acid is synthesized by glutamic acid decarboxylase, ...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1969
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.22.287